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CAS No. | 488793-85-7 | Cat. No. | BCP17386 |
Name | ARN272 | ||
Synonyms | ARN-272;ARN 272; | ||
SMILES | C1=CC=C(C=C1)NC(=O)C2=CC=C(C=C2)NC3=NNC(=C4C=CC(=O)C=C4)C5=CC=CC=C53 | ||
Chemical Name | |||
Formula | C27H20N4O2 | M. Wt | 432.47 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ARN 272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50 = 1.8 μM); cytosolic variant of FAAH-1 that binds anandamide. Attenuates anandamide internalization and deactivation in vitro and in vivo respectively. Exhibits analgesic effects in rodent models of CB1-mediated nociceptive and inflammatory pain. |
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