曲非奈肽
| CAS号 | 853400-76-7 | 货号 | BCP17581 |
| 中文名 | 曲非奈肽 | ||
| 英文名 | Trofinetide | ||
| 中文别名 | |||
| 英文别名 | NNZ-2566; NNZ 2566; NNZ2566; | ||
| 分子式 | C13H21N3O6 | 分子量 | 315.32 |
| 生物活性 | Trofinetide, also known as NNZ-2566, is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant. NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury. NNZ-2566 demonstrates neuroprotective efficacy in models of traumatic brain injury. NNZ-2566 significantly decreases injury-induced upregulation of inflammatory cytokines including TNF-α, IFN-γ, and IL-6. NNZ-2566 is a potential therapeutic agent for fragile X syndrome. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | Others | ||
结构式
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