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CAS号 | 853400-76-7 | 货号 | BCP17581 |
中文名 | 曲非奈肽 | ||
英文名 | Trofinetide | ||
中文别名 | |||
英文别名 | NNZ-2566; NNZ 2566; NNZ2566; | ||
SMILES | CC1(CCCN1C(=O)CN)C(=O)NC(CCC(=O)O)C(=O)O | ||
化学名称 | |||
分子式 | C13H21N3O6 | 分子量 | 315.32 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Trofinetide, also known as NNZ-2566, is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant. NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury. NNZ-2566 demonstrates neuroprotective efficacy in models of traumatic brain injury. NNZ-2566 significantly decreases injury-induced upregulation of inflammatory cytokines including TNF-α, IFN-γ, and IL-6. NNZ-2566 is a potential therapeutic agent for fragile X syndrome. |
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