Necrosulfonamide

CAS No.	432531-71-0	Cat. No.	BCP18373
Name	Necrosulfonamide
Synonyms	(E)-N-[4-[(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophen-2-yl)prop-2-enamide;
Formula	C18H15N5O6S2	M. Wt	461.47

Description	Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.
Pathways	MAPK Pathway
Targets	MLK

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