Necrosulfonamide
Data Sheet
For research use only. Not for human use.
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| CAS No. | 432531-71-0 | Cat. No. | BCP18373 |
| Name | Necrosulfonamide | ||
| Synonyms | (E)-N-[4-[(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophen-2-yl)prop-2-enamide; | ||
| SMILES | O=C(NC1=CC=C(S(=O)(NC2=NC=CN=C2OC)=O)C=C1)/C=C/C3=CC=C([N+]([O-])=O)S3 | ||
| Chemical Name | |||
| Formula | C18H15N5O6S2 | M. Wt | 461.47 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway. | ||
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