MK-4101
| CAS No. | 935273-79-3 | Cat. No. | BCP18385 |
| Name | MK-4101 | ||
| Synonyms | MK4101;MK 4101; | ||
| Formula | C24H24F5N5O | M. Wt | 493.47 |
| Description | MK-4101 is a potent and selective inhibitor of the Hedgehog Pathway. MK-401 Is Highly Active against Medulloblastoma and Basal Cell Carcinoma. MK-4101 showed anti-tumor activity through the inhibition of proliferation and induction of extensive apoptosis in tumor cells. MK-4101 was highly efficacious against primary medulloblastoma and BCC developing in the cerebellum and skin of Ptch1(+/-) mice. MK-4101 targets the Hh pathway in tumor cells, showing the maximum inhibitory effect on Gli1 MK-4101 also induced deregulation of cell cycle and block of DNA replication in tumors. | ||
| Pathways | GPCR/G Protein Wnt/Stem Cell | ||
| Targets | Smoothened/Smo Hedgehog | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.