PF-03758309 hydrochloride salt
| CAS No. | 1279034-84-2 | Cat. No. | BCP24749 |
| Name | PF-03758309 hydrochloride salt | ||
| Synonyms | PF-03758309 hydrochloride;PF-3758309 hydrochloride; | ||
| Formula | C25H31ClN8OS | M. Wt | 527.09 |
| Description | PF-3758309 hydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 hydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | PAK | ||
Structure
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