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PF-03758309 hydrochloride salt Chemical Structure

PF-03758309 hydrochloride salt

Data Sheet For research use only. Not for human use.
Cat. No. :BCP24749CAS No. :1279034-84-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1279034-84-2 Cat. No. BCP24749
Name PF-03758309 hydrochloride salt
Synonyms PF-03758309 hydrochloride;PF-3758309 hydrochloride;
SMILES CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)NC(CN(C)C)C5=CC=CC=C5)SC=C2.Cl
Chemical Name
Formula C25H31ClN8OS M. Wt 527.09
Purity 98% Storage Store at 4-8°C
Description PF-3758309 hydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 hydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation.
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