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CAS No. | 1279034-84-2 | Cat. No. | BCP24749 |
Name | PF-03758309 hydrochloride salt | ||
Synonyms | PF-03758309 hydrochloride;PF-3758309 hydrochloride; | ||
SMILES | CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)NC(CN(C)C)C5=CC=CC=C5)SC=C2.Cl | ||
Chemical Name | |||
Formula | C25H31ClN8OS | M. Wt | 527.09 |
Purity | 98% | Storage | Store at 4-8°C |
Description | PF-3758309 hydrochloride is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 hydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation. |
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