URB602
| CAS No. | 565460-15-3 | Cat. No. | BCP19101 |
| Name | URB602 | ||
| Synonyms | URB-602;URB 602; | ||
| Formula | C19H21NO2 | M. Wt | 295.38 |
| Description | URB602 is a selective, noncompetitive monoacylglycerol lipase (MAGL) inhibitor with IC50 of 28 uM against rat brain MAGL; elevates 2-AG levels and enhances 2-AG-mediated signaling in neurons, prolongs endocannabinoid-mediated changes in synaptic strength in acutely dissected rat hippocampal slices; showed anti-inflammatory and anti-nociceptive effect in murine model of acute inflammation. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | MAGL | ||
Structure
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