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URB602 Chemical Structure

URB602

Data Sheet For research use only. Not for human use.
Cat. No. :BCP19101CAS No. :565460-15-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 565460-15-3 Cat. No. BCP19101
Name URB602
Synonyms URB-602;URB 602;
SMILES O=C(OC1CCCCC1)NC2=CC(C3=CC=CC=C3)=CC=C2
Chemical Name
Formula C19H21NO2 M. Wt 295.38
Purity 98% Storage Store at 4-8°C
Description URB602 is a selective, noncompetitive monoacylglycerol lipase (MAGL) inhibitor with IC50 of 28 uM against rat brain MAGL; elevates 2-AG levels and enhances 2-AG-mediated signaling in neurons, prolongs endocannabinoid-mediated changes in synaptic strength in acutely dissected rat hippocampal slices; showed anti-inflammatory and anti-nociceptive effect in murine model of acute inflammation.
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