BMS-599626
| CAS No. | 714971-09-2 | Cat. No. | BCP19580 |
| Name | BMS-599626 | ||
| Synonyms | BMS599626;AC480;BMS 599626;AC-480;AC 480; | ||
| Formula | C27H27FN8O3 | M. Wt | 530.55 |
| Description | BMS-599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50 =22, 32 and 190 nM, respectively) with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR HER2 | ||
Structure
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