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BMS-599626 Chemical Structure

BMS-599626

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP19580CAS No. ：714971-09-2Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 714971-09-2 Cat. No. BCP19580
Name BMS-599626
Synonyms BMS599626;AC480;BMS 599626;AC-480;AC 480;
SMILES CC1=C2C(=NC=NN2C=C1NC(=O)OCC3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F
Chemical Name
Formula C27H27FN8O3 M. Wt 530.55
Purity 98% Storage Store at 4-8°C
Description BMS-599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50 =22, 32 and 190 nM, respectively) with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.
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