Eltanexor
| CAS No. | 1642300-52-4 | Cat. No. | BCP24993 |
| Name | Eltanexor | ||
| Synonyms | KPT-8602; KPT8602; KPT 8602; | ||
| Formula | C17H10F6N6O | M. Wt | 428.30 |
| Description | Eltanexor, also known as KPT-8602, is a second-generation exportin-1 inhibitor. KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia. KPT-8602 is well tolerated and highly active against AML blasts and leukemia-initiating cells. Eltanexor shows improved efficacy and in vivo tolerability in hematological malignancies. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | CRM1 | ||
Structure
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