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CAS No. | 1642300-52-4 | Cat. No. | BCP24993 |
Name | Eltanexor | ||
Synonyms | KPT-8602; KPT8602; KPT 8602; | ||
SMILES | C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C2=NN(C=N2)C=C(C3=CN=CN=C3)C(=O)N | ||
Chemical Name | |||
Formula | C17H10F6N6O | M. Wt | 428.30 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Eltanexor, also known as KPT-8602, is a second-generation exportin-1 inhibitor. KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia. KPT-8602 is well tolerated and highly active against AML blasts and leukemia-initiating cells. Eltanexor shows improved efficacy and in vivo tolerability in hematological malignancies. |
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