CRT0066101 dihydrochloride
| CAS No. | 1883545-60-5 | Cat. No. | BCP19777 |
| Name | CRT0066101 dihydrochloride | ||
| Synonyms | CRT0066101 2HCl;CRT 0066101; CRT-0066101; CRT0066101; | ||
| Formula | C18H22N6O.2HCl | M. Wt | 411.33 |
| Description | CRT 0066101 is a potent inhibitor of protein kinase D (PKD). It inhibits all PKD isoforms (IC50 values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively). CRT 0066101 exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCα, MEK, ERK, c-Raf and c-Src. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | PKD | ||
Structure
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