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CRT0066101 dihydrochloride Chemical Structure

CRT0066101 dihydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP19777CAS No. :1883545-60-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1883545-60-5 Cat. No. BCP19777
Name CRT0066101 dihydrochloride
Synonyms CRT0066101 2HCl;CRT 0066101; CRT-0066101; CRT0066101;
SMILES CCC(CNC1=NC(=NC=C1)C2=C(C=CC(=C2)C3=CN(N=C3)C)O)N.Cl.Cl
Chemical Name
Formula C18H22N6O.2HCl M. Wt 411.33
Purity 98% Storage Store at 4-8°C
Description CRT 0066101 is a potent inhibitor of protein kinase D (PKD). It inhibits all PKD isoforms (IC50 values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively). CRT 0066101 exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCα, MEK, ERK, c-Raf and c-Src.
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