Rogaratinib
| CAS No. | 1443530-05-9 | Cat. No. | BCP25142 |
| Name | Rogaratinib | ||
| Synonyms | BAY1163877; BAY-1163877; BAY 1163877; | ||
| Formula | C23H26N6O3S | M. Wt | 466.56 |
| Description | Rogaratinib, also known as BAY-1163877, is an aberrant fibroblast growth factor receptor (FGFR) inhibitor. Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity. FGFRs are a family of receptor tyrosine kinases, which may be upregulated in various tumor cell types and may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | FGFR | ||
Structure
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