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Rogaratinib Chemical Structure

Rogaratinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP25142CAS No. :1443530-05-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1443530-05-9 Cat. No. BCP25142
Name Rogaratinib
Synonyms BAY1163877; BAY-1163877; BAY 1163877;
SMILES CC1=CC2=C(C(=C1)OC)SC(=C2)C3=C4C(=NC=NN4C(=C3COC)CN5CCNC(=O)C5)N
Chemical Name
Formula C23H26N6O3S M. Wt 466.56
Purity 98% Storage Store at 4-8°C
Description Rogaratinib, also known as BAY-1163877, is an aberrant fibroblast growth factor receptor (FGFR) inhibitor. Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity. FGFRs are a family of receptor tyrosine kinases, which may be upregulated in various tumor cell types and may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival.
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