CC122
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CAS No. | 1015474-32-4 | Cat. No. | BCP15938 |
Name | CC122 | ||
Synonyms | CC-122;CC 122;Avadomide; | ||
SMILES | O=C(C(N1C(C)=NC2=C(C(N)=CC=C2)C1=O)CC3)NC3=O | ||
Chemical Name | |||
Formula | C14H14N4O3 | M. Wt | 286.29 |
Purity | 98% | Storage | Store at 4-8°C |
Description | CC-122 is an orally available pleiotropic pathway modulator with potential antineoplastic activity. CC-122 mimics an interferon response and has antitumor activity in DLBCL CC-122 binds Cereblon (CRBN) and promotes degradation of Aiolos and Ikaros in diffuse large B-cell lymphoma (DLBCL) and T cells in vitro, in vivo, and in patients, resulting in both cell autonomous as well as immunostimulatory effects. |
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