AM580
Data Sheet
For research use only. Not for human use.
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| CAS No. | 102121-60-8 | Cat. No. | BCP03051 |
| Name | AM580 | ||
| Synonyms | AM-580;AM 580; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C22H25NO3 | M. Wt | 351.44 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Studies indicate that RARα increases the signaling of the RARα receptor to prevent intracellular and extracellular Amyloid β accumulation. In addition, this receptor increases the expression of disintegrin and metalloprotease. Since Amyloid β accumulation is a major finding in Alzheimer's disease (AD), AM 580 can be used to study this disease in vitro. AM 580 also induces the functions of IL-4, IL-5 and IL-13 and suppresses the production of IL-12 and IFNγ. Alternate studies suggest that AM 580 inhibits tumor proliferation, via reducing the level of RARγ. AM 580 is an activator of RAR β and RAR γ. | ||
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