Mizolastine

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP06981CAS No. ：108612-45-9Purity：98%

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CAS No.	108612-45-9	Cat. No.	BCP06981
Name	Mizolastine
Synonyms	Mizollen;
SMILES
Chemical Name
Formula	C24H25FN6O	M. Wt	432.49
Purity	98%	Storage	Store at 4-8°C
Description	Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. It does not prevent the actual release of histamine from mast cells, just prevents it binding to receptors. Side effects can include dry mouth and throat. Mizolastine has demonstrated antiallergic effects in animals and healthy volunteers and anti-inflammatory activity in animal models. Double-blind trials have shown mizolastine to be significantly more effective than placebo and as effective as other second generation antihistamine agents, such as loratadine or cetirizine, in the management of patients with perennial or seasonal allergic rhinitis and in patients with chronic idiopathic urticaria. Available data also suggest that prophylactic administration of mizolastine is significantly more effective than placebo and as effective as prophylactic terfenadine in delaying the onset of symptoms of seasonal allergic rhin