Lestaurtinib
Data Sheet
For research use only. Not for human use.
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| CAS No. | 111358-88-4 | Cat. No. | BCP06977 |
| Name | Lestaurtinib | ||
| Synonyms | CEP-701; CEP701; CEP 701; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C26H21N3O4 | M. Wt | 439.46 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3 and < 25 nM respectively) that prevents STAT5 phosphorylation (IC50 = 20 - 30 nM). Exhibits antiproliferative activity in vitro (IC50 = 30 - 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disorders in vivo. | ||
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