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Gamitrinib Chemical Structure

Gamitrinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP24917CAS No. :1131626-46-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1131626-46-4 Cat. No. BCP24917
Name Gamitrinib
Synonyms Gamitrinib TPP;G-TPP;
SMILES
Chemical Name
Formula C52H65N3O8P M. Wt 890.85
Purity 98% Storage Store at 4-8°C
Description G-TPP is a mitochondria-targeted Hsp90 inhibitor that increases cell death in HeLa and MCF7 cells, consistently inhibits cell death induced by oxidative stress and mitochondrial dysfunction induced by PINK1 mutation in mouse embryonic fibroblast cells and DA cell models such as SH-SY5Y and SN4741 cells. Additionally, G-TPP also suppresses the defective locomotive activity and DA neuron loss in Drosophila PINK1 null mutants.
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