ZK200775 hydrate
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1255517-78-2 | Cat. No. | BCP16453 |
| Name | ZK200775 hydrate | ||
| Synonyms | Fanapanel hydrate;MPQX hydrate;ZK-200775 hydrate; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C14H17F3N3O7P | M. Wt | 427.27 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: In the cortical slice preparation assay, ZK200775 gave Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. In the spreading depression assay, it gave IC50 values of 200 nM, 76 nM, 13 μM, and 18 μM against quisqualate, kainate, NMDA, and glycine. in vivo: ZK200775 elevated the threshold for AMPA- and kainate-induced clonic seizures in mice with a THRD50 (threshold dose) of 2.9 (1.7–4.6) and 1.6 (1.3–2.0) mg/kg i.v., whereas the threshold for NMDA-induced seizures was elevated only in doses, THRD50 of 24.1 (21.9–26.5) mg/kg i.v., which affected motor coordination in the rotating rod, ED50 14.6 (12.1–17.6) mg/kg. ZK200775 in doses of 10 and 30 mg/kg i.v. reduced muscle tone in genetically spastic rats . ZK200775 (3.0 but not 1.5 or 6.0 mg/kg) significantly decreased the nicotine-induced (0.6 mg/kg) DA release in the NAcc and nicotine-stimulated LMA. ZK200775 (1.5, 3.0, 6.0 mg/kg) alone influenced neither DA release nor LMA. ZK200775 show | ||
Recommend Products
More >
-
Dextromethadone
Cat. No.：BCP49227
No.：5653-80-5
Product Details -
Philanthotoxin 433 tris(trifluoroacetate) salt
Cat. No.：BCP49022
No.：276684-27-6
Product Details -
-
-
Tulrampator
Cat. No.：BCP44153
No.：1038984-31-4
Product Details -
Dimiracetam
Cat. No.：BCP44036
No.：126100-97-8
Product Details -
-
Caroverine hydrochloride
Cat. No.：BCP43849
No.：55750-05-5
Product Details -
-
Sepimostat
Cat. No.：BCP38995
No.：103926-64-3
Product Details -
D(-)-Glutamic acid
Cat. No.：BCP38959
No.：6893-26-1
Product Details -
-
Spermidine trihydrochloride
Cat. No.：BCP36231
No.：334-50-9
Product Details -
Dizocilpine
Cat. No.：BCP34654
No.：77086-21-6
Product Details -
-
AMPA/kainate antagonist-1
Cat. No.：BCP34464
No.：732277-05-3
Product Details -
AMPA/kainate antagonist-2
Cat. No.：BCP34146
No.：923271-87-8
Product Details -
-
DNQX disodium salt
Cat. No.：BCP33086
No.：1312992-24-7
Product Details -
Perampanel 3/4 hydrate
Cat. No.：BCP24265
No.：1571982-04-1
Product Details
Tags:ZK200775 hydrate supplier,ZK200775 hydrate purchase,ZK200775 hydrate manufacturer,ZK200775 hydrate distributor,ZK200775 hydrate cost,ZK200775 hydrate buy,ZK200775 hydrate for sale