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CAS No. | 1257044-40-8 | Cat. No. | BCP06811 |
Name | Venetoclax | ||
Synonyms | GDC-0199; ABT199; ABT199; GDC0199; GDC 0199;ABT-199; | ||
SMILES | CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C | ||
Chemical Name | |||
Formula | C45H50ClN7O7S | M. Wt | 868.44 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process. Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic lymphoma. |
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