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Venetoclax Chemical Structure

Venetoclax

Data Sheet For research use only. Not for human use.
Cat. No. :BCP06811CAS No. :1257044-40-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1257044-40-8 Cat. No. BCP06811
Name Venetoclax
Synonyms GDC-0199; ABT199; ABT199; GDC0199; GDC 0199;ABT-199;
SMILES CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C
Chemical Name
Formula C45H50ClN7O7S M. Wt 868.44
Purity 98% Storage Store at 4-8°C
Description Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process. Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic lymphoma.
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