FLT3-IN-1
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CAS No. | 1370256-78-2 | Cat. No. | BCP15716 |
Name | FLT3-IN-1 | ||
Synonyms | FLT3-IN1;FLT3IN1;SKLB4771; SKLB-4771; SKLB 4771; | ||
SMILES | |||
Chemical Name | |||
Formula | C25H27N7O3S2 | M. Wt | 537.66 |
Purity | 98% | Storage | Store at 4-8°C |
Description | FLT3-IN-1, also known as SKLB4771, is a potent and selective FLT3 inhibitor potentially for the treatment of cutaneous inflammation and psoriasis-like symptoms of disease. Mechanistic studies indicated that SKLB4771 treatment significantly decreased the number and activation of pDCs and mDCs in vitro and in vivo, and subsequent T-cell cascade reactions mediated by Th1/Th17 pathways. |
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