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FLT3-IN-1 Chemical Structure

FLT3-IN-1

Data Sheet For research use only. Not for human use.
Cat. No. :BCP15716CAS No. :1370256-78-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1370256-78-2 Cat. No. BCP15716
Name FLT3-IN-1
Synonyms FLT3-IN1;FLT3IN1;SKLB4771; SKLB-4771; SKLB 4771;
SMILES
Chemical Name
Formula C25H27N7O3S2 M. Wt 537.66
Purity 98% Storage Store at 4-8°C
Description FLT3-IN-1, also known as SKLB4771, is a potent and selective FLT3 inhibitor potentially for the treatment of cutaneous inflammation and psoriasis-like symptoms of disease. Mechanistic studies indicated that SKLB4771 treatment significantly decreased the number and activation of pDCs and mDCs in vitro and in vivo, and subsequent T-cell cascade reactions mediated by Th1/Th17 pathways.
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