BIX01294 hydrochloride
Data Sheet
For research use only. Not for human use.
Get Quotation Now Tel: 0086-13026320035 or orders@biochempartner.com
Real-Time Inquiry ×
* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1392399-03-9 | Cat. No. | BCP14567 |
| Name | BIX01294 hydrochloride | ||
| Synonyms | BIX-01294 hydrochloride;BIX 01294 hydrochloride; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C28H38N6O2•3HCl | M. Wt | 600.02 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BIX-01294 specifically inhibited G9a (H3K9me2) and, to a lesser extent, the closely related GLP enzyme (primarily H3K9me3), with an IC50 of 1.7 μM for G9a and 38 μM for GLP. BIX-01294 inhibits G9a in an uncompetitive manner with SAM. BIX-01294 (4.1μM) reduces H3K9me2 Levels in Bulk Histone Preparations from wt ES cells, mouse embryonic fibroblasts and HeLa cells, but not in G9a deficient stem cells. BIX-01294 is a valuable inhibitor for the transient modulation of chromosomal H3K9me2. BIX-01294 Reduces H3K9me2 at Several G9a Target Genes including Bim1 and Serac1. BIX01294 could reactivate expression of HIV-1 from latently infected cells such as ACH-2 and OM10.1. | ||
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.
Recommend Products
More >
Tags:BIX01294 hydrochloride supplier,BIX01294 hydrochloride purchase,BIX01294 hydrochloride manufacturer,BIX01294 hydrochloride distributor,BIX01294 hydrochloride cost,BIX01294 hydrochloride buy,BIX01294 hydrochloride for sale