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CAS No. | 1450644-28-6 | Cat. No. | BCP17389 |
Name | NU 9056 | ||
Synonyms | NU-9056;NU9056; | ||
SMILES | C1=C(SN=C1)SSC2=CC=NS2 | ||
Chemical Name | |||
Formula | C6H4N2S4 | M. Wt | 232.37 |
Purity | 98% | Storage | Store at 4-8°C |
Description | NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation. |
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