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Capecitabine Chemical Structure

Capecitabine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01787CAS No. :154361-50-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 154361-50-9 Cat. No. BCP01787
Name Capecitabine
Synonyms Xeloda;Ro 09-1978;Ro-09-1978;Ro091978;Ro 091978000; Ro-091978000; Ro091978000;
SMILES C[C@@H]1[C@]([C@]([C@](N2C(N=C(C(F)=C2)NC(OCCCCC)=O)=O)O1)O)O
Chemical Name
Formula C15H22FN3O6 M. Wt 359.35
Purity 98% Storage Store at 4-8°C
Description Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.
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