Cromolyn sodium
Data Sheet
For research use only. Not for human use.
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| CAS No. | 15826-37-6 | Cat. No. | BCP12933 |
| Name | Cromolyn sodium | ||
| Synonyms | Disodium Cromoglycate;Gynazole; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H14O11.2Na | M. Wt | 512.33 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Cromolyn sodium is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack. Pretreatment of IIR mice with Cromolyn sodium prior to ischemia exhibited no changes of ET-1 levels, injury score and inflammation (P>0.05, PreCr vs. M groups). In conclusion, administration of Cromolyn sodium after reperfusion, but not prior to ischemia, attenuates IIRI by downregulating ET-1 and suppressing sustained MC activation . cromolyn sodium has a role in the prevention of Chronic lung disease(CLD). Cromolyn sodium cannot be recommended for the prevention of CLD in preterm infants . | ||
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