Talampanel
Data Sheet
For research use only. Not for human use.
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| CAS No. | 161832-65-1 | Cat. No. | BCP07340 |
| Name | Talampanel | ||
| Synonyms | LY300164; LY 300164; LY-300164; GYKI53773; Gyki 53405; Gyki-53405; LY293606; LY-293606; LY 293606; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C19H19N3O3 | M. Wt | 337.37 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Talampanel, also known as LY300164 and GYKI-53773, is a glutamate receptor inhibitor with anti-seizure activity. Talampanel is also an orally active, potent and selective AMPA-receptor antagonist, and can noncompetitively bind to the AMPA subtype of glutamate excitatory amino acid receptors and may inhibit the growth of gliomas by interfering with neurotransmitters involved in brain tumor growth. This agent may also protect against traumatic brain injury. Talampanel (GYKI 53405) is being investigated for the treatment of epilepsy, malignant gliomas and amyotrophic lateral sclerosis (ALS). As of May 2010, results from the trial for ALS have been found negative. | ||
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