TAPI1
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 163847-77-6 | Cat. No. | BCP12888 |
| Name | TAPI1 | ||
| Synonyms | TAPI-1;TAPI 1; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C26H37N5O5 | M. Wt | 499.6 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | TAPI-1 inhibited LL-37-induced TGF-α production, EGFR activation and subsequent MUC5AC mucin production, whereas TGF-α-neutralizing antibody, but not AR- or HB-EGF-neutralizing antibody, inhibited LL-37-induced EGFR activation and subsequent MUC5AC mucin production in NCI-H292 cells. Using the TNF-alpha converting enzyme (TACE) inhibitor, TAPI-1, TPA-stimulated TNFalpha shedding could be completely prevented in PKCepsilon transgenic mice and isolated keratinocytes. Pretreatment with antibody against FcγRII or with CD32 siRNA, p47(phox) siRNA, apocynin, N-acetylcysteine, tumor necrosis factor-α protease inhibitor 1 (TAPI-1) or TACE siRNA attenuated sLOX-1 release induced by CRP. CRP also elevated serum sLOX-1 levels in a rabbit model of atherosclerosis . | ||
Recommend Products
More >
-
-
-
2'-Fucosyllactose
Cat. No.：BCP47768
No.：41263-94-9
Product Details -
ONC-201 Dihydrochloride
Cat. No.：BCP46830
No.：1638178-82-1
Product Details -
-
-
(Rac)-Benpyrine
Cat. No.：BCP37768
No.：1333714-43-4
Product Details -
-
-
-
-
AX-024 hydrochloride
Cat. No.：BCP30050
No.：1704801-24-0
Product Details -
-
-
-
-
Tpl2 Kinase Inhibitor
Cat. No.：BCP16321
No.：871307-18-5
Product Details -
-
Etanercept
Cat. No.：BCP12862
No.：185243-69-0
Product Details -
Methylthiouracil
Cat. No.：BCP21374
No.：56-04-2
Product Details
Tags:TAPI1 supplier,TAPI1 purchase,TAPI1 manufacturer,TAPI1 distributor,TAPI1 cost,TAPI1 buy,TAPI1 for sale