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Betamethasone Chemical Structure

Betamethasone

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02020CAS No. :378-44-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 378-44-9 Cat. No. BCP02020
Name Betamethasone
Synonyms NCS-39470;NCS 39470;NCS39470;SCH-4831;SCH 4831;SCH4831;
SMILES
Chemical Name
Formula C22H29FO5 M. Wt 504.59
Purity 98% Storage Store at 4-8°C
Description Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Unlike other drugs with these effects, betamethasone does not cause water retention. The median (range) IC50 value for betamethasone butyrate propionate evaluated in the streptococcal pyrogenic enterotoxin A-stimulated peripheral-blood mononuclear cells was 291.6 (0.001-1171.5) ng/ml, which was significantly higher than the value 0.072 (0.01-222.5) ng/ml found in concanavalin A-stimulated peripheral-blood mononuclear cells (P=0.0245). Children exposed prenatally to betamethasone (n = 121) did not differ in systolic or diastolic blood pressure from children exposed to placebo (n = 102) (mean difference: systolic: -1.6 mm Hg; 95% confidence interval: -4.1 to 0.8 mm Hg; diastolic: -0.3 mm Hg; 95% confidence interval: -2.5 to 1.8 mm Hg) . Intra-articular corticosteroid injection of 6 mg of betamethasone acetate/betamethasone sodium phosphate at the knee joint was not significantly asso
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