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CAS No. | 444805-28-1 | Cat. No. | BCP08580 |
Name | Brincidofovir | ||
Synonyms | CMX001; CMX 001; CMX-001; HDP-cidofovir; Hexadecyloxypropyl-cidofovir; HDP-CDV; HDPCDV; | ||
SMILES | OC[C@H](CN1C=CC(N)=NC1=O)OCP(O)(OCCCOCCCCCCCCCCCCCCCC)=O | ||
Chemical Name | |||
Formula | C27H52N3O7P | M. Wt | 561.69 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Brincidofovir, also known as CMX001, HDP-CDV and HDPCDV, is DNA polymerase inhibitor potentially for the treatment of cytomegalovirus, adenovirus, smallpox, and ebolavirus infections. Brincidofovir is a prodrug of cidofovir. Conjugated to a lipid, the compound is designed to release cidofovir intracellularly, allowing for higher intracellular and lower plasma concentrations of cidofovir, effectively increasing its activity against dsDNA viruses, as well as oral bioavailability. |
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