Acrolein

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP02914CAS No. ：4460-86-0Purity：98%

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CAS No.	4460-86-0	Cat. No.	BCP02914
Name	Acrolein
Synonyms	Asaronaldehyde;Asarylaldehyde;NSC 89299;Propenal;
SMILES
Chemical Name
Formula	C10H12O4	M. Wt	196.2
Purity	98%	Storage	Store at 4-8°C
Description	Asaraldehyde is found to be the most abundant constituent, but is totally absent in its cultured broth and its natural host, C. kanehirae wood. On feeding with the acid-digested sawdust of C. kanehirae wood or vanillin to the broth for culture, Asaraldehyde is produced in both cultured broths. Asaraldehyde shows 3.32% of prostaglandin H endoperoxide synthase-1 (COX-1) inhibitory activity and 52.69% prostaglandin H endoperoxide synthase-2 (COX-2) inhibitory activity, respectively at 100 mg/mL. Asaraldehyde shows selectivity towards COX-2 enzyme inhibition at 100 μg/mL. The COX-2/COX-1 ratio for Asaraldehyde is 17.68 at 100 μg/mL compared to solvent control.Asaraldehyde down-regulates C/EBPβ, C/EBPδ, and C/EBPα. Asaraldehyde suppresses expression of PPARγ1 and PPARγ2. Asaraldehyde also significantly suppresses the expression of acetyl-CoA carboxylase (ACC).