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CAS No. | 747412-49-3 | Cat. No. | BCP01827 |
Name | Luminespib | ||
Synonyms | AUY922;NVP-AUY922;VER-52296;AUY 922;AUY-922;VER 52296;VER52296; | ||
SMILES | CCNC(=O)C1=NOC(=C1C2=CC=C(C=C2)CN3CCOCC3)C4=CC(=C(C=C4O)O)C(C)C | ||
Chemical Name | |||
Formula | C26H31N3O5 | M. Wt | 465.54 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Luminespib is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins. |
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