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Obatoclax Chemical Structure

Obatoclax

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP20625CAS No. ：803712-67-6Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 803712-67-6 Cat. No. BCP20625
Name Obatoclax
Synonyms GX 015-070; GX015-070; GX-015-070; GX 015070; GX015070; GX-015070; GX 015-070; GX15-070;
SMILES COC1=CC(C2=CC3=CC=CC=C3N2)=N/C1=C/C4=C(C=C(C)N4)C
Chemical Name
Formula C20H19N3O M. Wt 317.38
Purity 98% Storage Store at 4-8°C
Description Obatoclax, also known as GX 015-070, a synthetic small-molecule inhibitor of the bcl-2 family of proteins with potential pro-apoptotic and antineoplastic activities. Obatoclax binds to members of the Bcl-2 protein family, preventing the binding of these anti-apoptotic proteins to the pro-apoptotic proteins Bax and Bak and so promoting the activation of the apoptotic pathway in Bcl-2-overexpressing cells. The Bcl-2 family of proteins (bcl-2, bcl-xl, bcl-w, and Mcl-1) are overexpressed in a wide variety of cancers, including those of the lymphatic system, breast, lung, prostate, and colon.
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