Cabozantinib
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 849217-68-1 | Cat. No. | BCP02591 |
| Name | Cabozantinib | ||
| Synonyms | XL 184;XL-184;XL184;BMS-907351;BMS 907351;BMS907351; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C28H24FN3O5 | M. Wt | 501.51 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | XL184 has weak inhibitory activity against RON and PDGFRβ with IC50 of 124 nM and 234 nM, respectivey, and has low activity against FGFR1 with IC50 of 5.294 μM.XL184 at low concentration (0.1-0.5 μM) is sufficient to induce marked inhibition of constitutive and inducible Met phosphorylation and its resultant downstream signaling in MPNST cells, and inhibit HGF-induced MPNST cell migration and invasion. XL184 also induces marked inhibition of Met and VEGFR2 phosphorylation in cytokine-stimulated human umbilical vein endothelial cells (HUVECs). Although XL-184 has no significant effect on MPNST cell growth at 0.1 μM, XL184 at 5-10 μM significantly inhibits the MPNST cell growth. | ||
Recommend Products
More >
-
Tuspetinib hydrate
Cat. No.：BCP49212
No.：2758339-04-5
Product Details -
HPK1-IN-2
Cat. No.：BCP48923
No.：2056122-11-1
Product Details -
FLT3-IN-16
Cat. No.：BCP48905
No.：298207-49-5
Product Details -
-
MAX-40279 hemifumarate
Cat. No.：BCP46381
No.：2388506-43-0
Product Details -
MAX-40279 hemiadipate
Cat. No.：BCP46003
No.：2388506-44-1
Product Details -
MAX-40279
Cat. No.：BCP46002
No.：2070931-57-4
Product Details -
FLT3-IN-3
Cat. No.：BCP45355
No.：2229050-90-0
Product Details -
-
-
UNC2025 hydrochloride
Cat. No.：BCP36467
No.：2070015-17-5
Product Details -
-
-
Donafenib
Cat. No.：BCP34023
No.：1130115-44-4
Product Details -
Emavusertib
Cat. No.：BCP33271
No.：1801344-14-8
Product Details -
-
CCT241736
Cat. No.：BCP29563
No.：1402709-93-6
Product Details -
-
-
Tags:Cabozantinib supplier,Cabozantinib purchase,Cabozantinib manufacturer,Cabozantinib distributor,Cabozantinib cost,Cabozantinib buy,Cabozantinib for sale