Tanzisertib
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CAS No. | 899805-25-5 | Cat. No. | BCP16541 |
Name | Tanzisertib | ||
Synonyms | CC 930;CC930;CC-930; | ||
SMILES | |||
Chemical Name | |||
Formula | C21H23F3N6O2 | M. Wt | 448.44 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Tanzisertib, also known as CC-930, is a potent, selective, and orally active JNK inhibitor with potential antifibrotic activity. CC-930 entered Phase I clinical trials. Tanzisertib may have potential use for prevention and treatment of dermal fibrosis. Selective inhibition of JNK by CC-930 exerted potent antifibrotic effects in vitro and in different models in vivo. JNK might thus be a novel molecular target for the treatment of fibrosis in SSc. |
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