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Tamibarotene Chemical Structure

Tamibarotene

Data Sheet For research use only. Not for human use.
Cat. No. :BCP07492CAS No. :94497-51-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 94497-51-5 Cat. No. BCP07492
Name Tamibarotene
Synonyms AM 80; AM-80; AM80;
SMILES
Chemical Name
Formula C22H25NO3 M. Wt 351.44
Purity 98% Storage Store at 4-8°C
Description Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.
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