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Acrolein Chemical Structure

Acrolein

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02914CAS No. :4460-86-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 4460-86-0 Cat. No. BCP02914
Name Acrolein
Synonyms Asaronaldehyde;Asarylaldehyde;NSC 89299;Propenal;
SMILES
Chemical Name
Formula C10H12O4 M. Wt 196.2
Purity 98% Storage Store at 4-8°C
Description Asaraldehyde is found to be the most abundant constituent, but is totally absent in its cultured broth and its natural host, C. kanehirae wood. On feeding with the acid-digested sawdust of C. kanehirae wood or vanillin to the broth for culture, Asaraldehyde is produced in both cultured broths. Asaraldehyde shows 3.32% of prostaglandin H endoperoxide synthase-1 (COX-1) inhibitory activity and 52.69% prostaglandin H endoperoxide synthase-2 (COX-2) inhibitory activity, respectively at 100 mg/mL. Asaraldehyde shows selectivity towards COX-2 enzyme inhibition at 100 μg/mL. The COX-2/COX-1 ratio for Asaraldehyde is 17.68 at 100 μg/mL compared to solvent control.Asaraldehyde down-regulates C/EBPβ, C/EBPδ, and C/EBPα. Asaraldehyde suppresses expression of PPARγ1 and PPARγ2. Asaraldehyde also significantly suppresses the expression of acetyl-CoA carboxylase (ACC).
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