罗西普托
| CAS号 | 782487-28-9 | 货号 | BCP26168 |
| 中文名 | 罗西普托 | ||
| 英文名 | Rosiptor | ||
| 中文别名 | 洛司普托; | ||
| 英文别名 | AQX-1125; AQX 1125; AQX1125; | ||
| 分子式 | C20H35NO2 | 分子量 | 321.51 |
| 生物活性 | Rosiptor, also known as AQX-1125, is an activator of SHIP1, which controls the PI3K cellular signaling pathway. If the PI3K pathway is overactive, immune cells can produce an abundance of pro-inflammatory signaling molecules and migrate to and concentrate in tissues, resulting in excessive or chronic inflammation. SHIP1 is predominantly expressed in cells derived from bone marrow tissues, which are mainly immune cells. Therefore drugs that activate SHIP1 can reduce the function and migration of immune cells and have an anti-inflammatory effect. By controlling the PI3K pathway, Rosiptor reduces immune cell function and migration by targeting a mechanism that has evolved in nature to maintain homeostasis of the immune system. | ||
| 上下游产品 | 782487-29-0（Rosiptor acetate） | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Phosphatase | ||
结构式
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