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Rosiptor 结构式

罗西普托

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP26168CAS号 :782487-28-9纯度:98%
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  • 基本信息与产品描述
CAS号 782487-28-9 货号 BCP26168
关联产品 782487-29-0(Rosiptor acetate)
中文名 罗西普托
英文名 Rosiptor
中文别名 洛司普托;
英文别名 AQX-1125; AQX 1125; AQX1125;
SMILES CC1(CCC(CC1CO)O)C2CCC3(C(C2CN)CCC3=C)C
化学名称
分子式 C20H35NO2 分子量 321.51
纯度 98% 配送 惯例下常温包邮
产品描述 Rosiptor, also known as AQX-1125, is an activator of SHIP1, which controls the PI3K cellular signaling pathway. If the PI3K pathway is overactive, immune cells can produce an abundance of pro-inflammatory signaling molecules and migrate to and concentrate in tissues, resulting in excessive or chronic inflammation. SHIP1 is predominantly expressed in cells derived from bone marrow tissues, which are mainly immune cells. Therefore drugs that activate SHIP1 can reduce the function and migration of immune cells and have an anti-inflammatory effect. By controlling the PI3K pathway, Rosiptor reduces immune cell function and migration by targeting a mechanism that has evolved in nature to maintain homeostasis of the immune system.
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