(R)-GSK-3685032
| CAS No. | 2170140-50-6 | Cat. No. | BCP45844 |
| Name | (R)-GSK-3685032 | ||
| Synonyms | (R)-GSK3685032;(R)-GSK 3685032; | ||
| Formula | C22H24N6OS | M. Wt | 420.53 |
| Description | (R)-GSK-3685032 is the R-enantiomer of GSK-3685032. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition. | ||
| Related Products | GSK3685032TFA（GSK3685032 TFA ） 2170137-61-6（GSK3685032） | ||
| Pathways | Epigenetics | ||
| Targets | DNA Methyltransferase | ||
Structure
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