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CAS No. | 2170140-50-6 | Cat. No. | BCP45844 |
Related Products | GSK3685032TFA(GSK3685032 TFA ) 2170137-61-6(GSK3685032) | ||
Name | (R)-GSK-3685032 | ||
Synonyms | (R)-GSK3685032;(R)-GSK 3685032; | ||
SMILES | |||
Chemical Name | |||
Formula | C22H24N6OS | M. Wt | 420.53 |
Purity | 98% | Storage | Store at 4-8°C |
Description | (R)-GSK-3685032 is the R-enantiomer of GSK-3685032. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition. |
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