Fostamatinib
CAS No. | 901119-35-5 | Cat. No. | BCP01871 |
Name | Fostamatinib | ||
Synonyms | R788;R7935788;R 788;R 7935788;R-788;R-7935788; | ||
Formula | C23H26FN6O9P | M. Wt | 580.46 |
Description | Fostamatinib, also known as R 788 and R-935788, is an orally active, potent and selective Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities. Fostamatinib is also a pro-drug of R-406. Fostamatinib inhibits Syk kinase-mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage. | ||
Related Products | 1025687-58-4(Fostamatinib disodium) 914295-16-2(Fostamatinib disodium hexahydrate) | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | Syk |
Structure
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