Fostamatinib

  • Chemical Properties
CAS No. 901119-35-5 Cat. No. BCP01871
Name Fostamatinib
Synonyms R788;R7935788;R 788;R 7935788;R-788;R-7935788;
Formula C23H26FN6O9P M. Wt 580.46
  • Biological Activity
Description Fostamatinib, also known as R 788 and R-935788, is an orally active, potent and selective Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities. Fostamatinib is also a pro-drug of R-406. Fostamatinib inhibits Syk kinase-mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage.
Related Products 1025687-58-4(Fostamatinib disodium) 914295-16-2(Fostamatinib disodium hexahydrate)
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Syk 

Structure

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