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Fostamatinib Chemical Structure

Fostamatinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01871CAS No. :901119-35-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 901119-35-5 Cat. No. BCP01871
Related Products 1025687-58-4(Fostamatinib disodium) 914295-16-2(Fostamatinib disodium hexahydrate)
Name Fostamatinib
Synonyms R788;R7935788;R 788;R 7935788;R-788;R-7935788;
SMILES COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O)(O)=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC
Chemical Name
Formula C23H26FN6O9P M. Wt 580.46
Purity 98% Storage Store at 4-8°C
Description Fostamatinib, also known as R 788 and R-935788, is an orally active, potent and selective Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities. Fostamatinib is also a pro-drug of R-406. Fostamatinib inhibits Syk kinase-mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage.
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