Fostamatinib
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CAS No. | 901119-35-5 | Cat. No. | BCP01871 |
Related Products | 1025687-58-4(Fostamatinib disodium) 914295-16-2(Fostamatinib disodium hexahydrate) | ||
Name | Fostamatinib | ||
Synonyms | R788;R7935788;R 788;R 7935788;R-788;R-7935788; | ||
SMILES | COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O)(O)=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC | ||
Chemical Name | |||
Formula | C23H26FN6O9P | M. Wt | 580.46 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Fostamatinib, also known as R 788 and R-935788, is an orally active, potent and selective Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities. Fostamatinib is also a pro-drug of R-406. Fostamatinib inhibits Syk kinase-mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage. |
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