扎布拉林
| CAS号 | 3690-10-6 | 货号 | BCP12209 |
| 中文名 | 扎布拉林 | ||
| 英文名 | Zebularine | ||
| 中文别名 | 2-嘧啶酮-B-核甙; | ||
| 英文别名 | NSC309132;NSC-309132;NSC 309132;4-Deoxyuridine; | ||
| 分子式 | C9H12N2O5 | 分子量 | 228.2 |
| 生物活性 | Zebularine is a synthetic cytidine analogue and a cytidine deaminase inhibitor with anticancer activity. Following metabolic activation by phosphorylation and incorporation into DNA, zebularine inhibits DNA methyltransferase through covalent complex formation between the enzyme and zebularine-substituted DNA, hence resulting in non-specific, genome-wide induction of demethylation including the removal of aberrant methylation of promoter regions of genes critical for normal cellular functions. | ||
| 信号通路 | Others Pathway Epigenetics | ||
| 靶 点 | DNA Methyltransferase Autophagy | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！