RWJ-58259
| CAS No. | 315203-31-7 | Cat. No. | BCP18032 |
| Name | RWJ-58259 | ||
| Synonyms | RWJ 58259;RWJ58259; | ||
| Formula | C40H42Cl2F2N8O3 | M. Wt | 791.72 |
| Description | RWJ-58259 is a potent and selective inhibitor of PAR-1 identified as part of a synthetic chemistry program based upon a de novo design approach. RWJ-58259 inhibited thrombin-induced platelet aggregation in human platelets with an IC50 of 0.37 μM without inhibiting thrombin's proteolytic activity or aggregation induced by other agonists. | ||
| Pathways | GPCR/G Protein | ||
| Targets | PAR | ||
Structure
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