RWJ-58259 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 315203-31-7 | Cat. No. | BCP18032 |
| Name | RWJ-58259 | ||
| Synonyms | RWJ 58259;RWJ58259; | ||
| SMILES | C1CCN(C1)CC2=NN(C3=C2C=CC(=C3)NC(=O)NC(CC4=CC(=C(C=C4)F)F)C(=O)NC(CCN)C(=O)NCC5=CC=CC=C5)CC6=C(C=CC=C6Cl)Cl | ||
| Chemical Name | |||
| Formula | C40H42Cl2F2N8O3 | M. Wt | 791.72 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | RWJ-58259 is a potent and selective inhibitor of PAR-1 identified as part of a synthetic chemistry program based upon a de novo design approach. RWJ-58259 inhibited thrombin-induced platelet aggregation in human platelets with an IC50 of 0.37 μM without inhibiting thrombin's proteolytic activity or aggregation induced by other agonists. | ||
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